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Oncogene-induced senescence has one of its prime characteristics altered chromatin structure typified by the presence of numerous DNA-dense structures called senescence-associated heterochromatin foci (SAHF).

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2001 Koman LA, Brashear A, Rosenfeld S, et al Botulinum toxin type a neuromuscular blockade in bknary treatment of equinus foot deformity in binary options jerusalem palsy: a multicenter, open-label clinical trial Jeruwalem 108(5):1062-71 2001 Zafonte RD, Munin MC Phenol and alcohol for the treatment of spasticity Phys Med Rehabil Clin N Am 12(4):817-832 2001 Molenaers G; Desloovere K; De Cat J; et al Single event multilevel botulinum toxin type A treatment and surgery: Similarities and differences Eur J Neurol;8(Suppl 5):88-97 1999 Molenaers G, Desloovere K, Eyssen M, et al Botulinum toxin type A treat- ment of cerebral palsy: An integrated approach Eur J Neurol jjerusalem 4):S51- S57 1999 Wissel J; Heinen F; Schenkel A; et al Botulinum toxin A in the manage- ment of spastic gait disorders in children and young adults with cerebral palsy: A randomized, double-blind study of high-dose versus low-dose treatment Neu- ropediatrics;30(3):120-124 1997 MF Brin: Botulinum Toxin: Chemistry, Pharmacology, Toxicity, and Immunol- ogy Muscle Nerve 20 (suppl 6): S146-S168.

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