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I-1 xv Index 383 R racemates, 62, 63 raloxifen, 254 ramipril, 124 ranitidine, 116, 168 rapid eye movement (REM) sleep, 222, 223 reactive hyperemia, 90, 91 receptor-mediated endo- cytosis, 26, 27 receptors, 20 drug binding, 56 types of, 6465 rectal administration, 12, 18, 19 reduction reactions, 36, 37 renal failure, prophylaxis, 158 renal tubular secretion, 40 renin, 124, 158 renin-angiotensin-aldoste- rone (RAA) system, 118, 125, 158 inhibitors of, 124125 reserpine, 96, 114 resistance, 266, 267 respiratory tract, 22 inhalation of drugs, 14, 15, 18, 19 retarded drug release, 10, 11 reteplase, 146 retrospective trials, 76 reverse transcriptase, 288 inhibitors, 288, 289 Reyes syndrome, 198 rheumatoid arthritis, 302, 320321 rhinitis, 324 ribonucleic acid (RNA), 274 synthesis inhibition, 298, 299 ribosomes, 276 ricinoleic acid, 174, 175 rifabutin, 274 rifampin, 267, 274, 280, 281 risk:benefit ratio, 70 risperidone, 238, 240 ritodrine, 126 ritonavir, 288 rocuronium, 184 rolitetracycline, 278 ropinirole, 188 rosiglitazone, 262 rough endoplasmic reticu- lum (rER), 32, 33 roundworms, 292, 293 S salazosulfapyridine, 272 salbutamol, 86, 328 salicylates, 200 salicylic acid, 34 see also acetylsalicylic acid salmeterol, 328 Salmonella typhi, 270, 271 saluretics, see diuretics saquinavir, 288, 289 sarcoplasmic reticulum, 182 Sarcoptes scabiei, 292 sartans, 124 Schistosoma, 292 schizophrenia, 118, 236, 237 Schmiedeberg, Oswald, 3 scopolamine, 106, 107, 240, 330 sea sickness, 106, 330, 331 sedation, 222, 226 scopolamine, 106 seizures, 190, 226 selectivity, lack of, 70, 71 selegiline, 88, 188 senna, 174, 176 sensitivity increased, 70, 71 variation, 52 sensitization, 72 serotonin, 88, 116118 actions, 116 neuronal reuptake, 230 platelet activation, 148, 150 receptors, 116, 230, 322 serotonin-selective reup- take inhibitors (SSRI), 230, 232 sertindole, 238 sertraline, 232 Sertümer, F.
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